Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891483 | 1.00 | DAO (0.48) | DAORARBRARGRXRARXRB | |
| SCHEMBL13305777 | 0.78 | DAO (0.42) | DAOGLATDP1IAPPPTGS1 | |
| SCHEMBL8948187 | 0.78 | DAO (0.42) | DAOGLATDP1IAPPPTGS1 | |
| SCHEMBL23093666 | 0.78 | DAO (0.41) | DAORARBRARGRXRARXRB | |
| SCHEMBL23093667 | 0.78 | DAO (0.41) | DAORARBRARGRXRARXRB | |
| SCHEMBL12919403 | 0.75 | GLA (0.40) | GLATDP1IAPPPTGS1GAA | |
| SCHEMBL1471364 | 0.75 | DAO (0.52) | DAORARBRARGRXRARXRB | |
| SCHEMBL23110162 | 0.75 | DAO (0.42) | DAORARBRARGRXRARXRB | |
| SCHEMBL27597008 | 0.74 | TTR (0.46) | DAOGAAKMT2AMAPTMEN1 | |
| SCHEMBL17344061 | 0.69 | TDP1 (0.55) | GLATDP1IAPPPTGS1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018462-A1 | QUINAZOLINONE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |