Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579565 | 1.00 | TSHR (0.59) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL17848566 | 1.00 | TSHR (0.59) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL28627520 | 1.00 | TSHR (0.59) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL689151 | 1.00 | TSHR (0.59) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL27857232 | 1.00 | TSHR (0.59) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL28995613 | 1.00 | TSHR (0.59) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL3092077 | 1.00 | TSHR (0.59) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL28745046 | 0.96 | TSHR (0.59) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL29008254 | 0.93 | TSHR (0.51) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL28407387 | 0.93 | TSHR (0.56) | TSHRNAAADGKARAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131776-B2 | Composition to improve cold flow properties of fuel oils | EVONIK OIL ADDITIVES GMBH (DE) | 2018-11-20 | — | — | US | disclosed |
| US-20120174474-A1 | COMPOSITION TO IMPROVE COLD FLOW PROPERTIES OF FUEL OILS | EVONIK ROHMAX ADDITIVES GMBH (DE) | 2012-07-12 | — | — | US | disclosed |
| EP-2305753-B1 | A composition to improve cold flow properties of fuel oils | EVONIK ROHMAX ADDITIVES GMBH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2305753-A1 | A composition to improve cold flow properties of fuel oils | Evonik RohMax Additives GmbH (DE) | 2011-04-06 | — | — | EP | disclosed |
| WO-2011035947-A1 | A COMPOSITION TO IMPROVE COLD FLOW PROPERTIES OF FUEL OILS | EVONIK ROHMAX ADDITIVES GMBH (DE) | 2011-03-31 | — | — | WO | disclosed |