Isophthalic Acid

Isophthalic Acid

SCHEMBL689179

Br.Br.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.68
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68
CA6 P23280 1/20 0.68
CA9 Q16790 1/20 0.68
TSHR P16473 2/20 0.63
DAO P14920 1/20 0.63
NAPRT Q6XQN6 1/20 0.63
KMO O15229 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2C9 P11712 1/20 0.62
HPGD P15428 1/20 0.62
HSD17B10 Q99714 1/20 0.62
UNG P13051 1/20 0.60
L3MBTL1 Q9Y468 2/20 0.59
ATM Q13315 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
FOLH1 Q04609 1/20 0.58
AKR1C3 P42330 1/20 0.58
TP53 P04637 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL1963275 1.00 CA12 (0.68) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL20500514 0.97 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL22462 0.97 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL147366 0.97 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL2512374 0.97 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL28462260 0.97 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL28756611 0.97 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL23035005 0.94 CA12 (0.68) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL7566218 0.94 CA12 (0.68) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL15571212 0.94 CA12 (0.68) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP claimed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO claimed
US-20240101751-A1 HOLLOW MICROBALLOON TOKUYAMA CORPORATION (JP) 2024-03-28 US disclosed
US-20230390890-A1 POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON TOKUYAMA CORPORATION (JP) 2023-12-07 US disclosed
EP-4286439-A1 HOLLOW MICROBALLOON Tokuyama Corporation (JP) 2023-12-06 EP disclosed
EP-4205904-A1 POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON Tokuyama Corporation (JP) 2023-07-05 EP disclosed
US-20230203234-A1 HOLLOW MICROBALLOONS TOKUYAMA CORPORATION (JP) 2023-06-29 US disclosed
US-20230151179-A1 HOLLOW MICROBALLOONS FOR CMP POLISHING PAD TOKUYAMA CORPORATION (JP) 2023-05-18 US disclosed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
WO-2022045018-A1 POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON 株式会社トクヤマ 2022-03-03 WO disclosed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP disclosed
EP-0173472-A2 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-03-05 EP disclosed
EP-0171155-A1 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-02-12 EP disclosed
EP-0171200-A2 Catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-02-12 EP disclosed
US-4565798-A COORDINATION CATALYSTS, TITANIUM, MAGNESIUM, SILICON COMPOUND TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-01-21 US disclosed
EP-0157472-A1 Process for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-10-09 EP disclosed
EP-0156512-A1 Process for preparing catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-10-02 EP disclosed
EP-0147053-A1 A catalyst and a process for polymerization of olefins Tonen Corporation (JP) 1985-07-03 EP disclosed
EP-0145368-A2 Process for producing propylene block copolymers TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-06-19 EP disclosed
US-4278786-A BIS/P-AMINOPHENOL ETHER OF A BISPHENOL HITACHI, LTD. (JP) 1981-07-14 US disclosed