Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897288 | 0.90 | EDNRA (0.65) | EDNRAAGTR1 | |
| SCHEMBL4771323 | 0.87 | EDNRA (0.79) | EDNRAAGTR1 | |
| SCHEMBL4771475 | 0.85 | EDNRA (0.76) | EDNRAAGTR1 | |
| SCHEMBL4769567 | 0.84 | EDNRA (0.74) | EDNRAAGTR1 | |
| SCHEMBL4773198 | 0.84 | EDNRA (0.74) | EDNRAAGTR1 | |
| SCHEMBL4769522 | 0.81 | EDNRA (1.00) | EDNRAAGTR1 | |
| SCHEMBL4769524 | 0.81 | EDNRA (0.69) | EDNRAAGTR1 | |
| SCHEMBL4771501 | 0.81 | EDNRA (1.00) | EDNRAAGTR1 | |
| SCHEMBL4769441 | 0.80 | EDNRA (1.00) | EDNRAAGTR1 | |
| SCHEMBL4764891 | 0.80 | EDNRA (0.67) | EDNRAAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835741-B2 | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-28 | — | — | US | disclosed |