SCHEMBL6892641

SCHEMBL6892641

COc1ccccc1C(c1ccccc1S)c1ccccc1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA12 O43570 1/20 0.50
CA4 P22748 1/20 0.50
CA14 Q9ULX7 1/20 0.50
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
ORAI1 Q96D31 1/20 0.42
ORAI2 Q96SN7 1/20 0.42
ORAI3 Q9BRQ5 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
ADRA2B P18089 1/20 0.41
PTGS1 P23219 1/20 0.41
ACHE P22303 1/20 0.41
HTT P42858 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066662 0.89 CA1 (0.63) CA1CA2CA7CA9CA12
SCHEMBL901122 0.81 MAPT (0.36) MAPT
SCHEMBL8179 0.79
SCHEMBL29518025 0.79
SCHEMBL303153 0.77 MEN1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL5583967 0.77 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL8866333 0.77 CA1 (0.60) CA1CA2CA7CA9CA12
Potassium SCHEMBL8866346 0.77 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL9505746 0.77 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL28115667 0.77 CA1 (0.60) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425417-A2 INTERACTION DETECTION ON SEVERAL PROBE ARRAYS Clondiag Chip Technologies GmbH (DE) 2004-06-09 EP disclosed
WO-2003018838-A2 INTERACTION DETECTION ON SEVERAL PROBE ARRAYS CLONDIAG CHIP TECHNOLOGIES GMBH (DE) 2003-03-06 WO disclosed