Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891505 | 0.91 | GRM2 (0.63) | GRM2CYP3A4 | |
| SCHEMBL1503062 | 0.82 | GRM2 (0.73) | GRM2CYP3A4 | |
| SCHEMBL6892456 | 0.81 | GRM2 (0.63) | GRM2CYP3A4 | |
| SCHEMBL6890239 | 0.79 | GRM2 (1.00) | GRM2CYP3A4 | |
| SCHEMBL6891642 | 0.79 | GRM2 (0.88) | GRM2CYP3A4 | |
| SCHEMBL6894487 | 0.79 | GRM2 (0.88) | GRM2CYP3A4 | |
| SCHEMBL1503015 | 0.78 | GRM2 (0.57) | GRM2CYP3A4 | |
| SCHEMBL6894123 | 0.77 | GRM2 (0.54) | GRM2CYP3A4 | |
| SCHEMBL14317237 | 0.76 | GRM2 (0.68) | GRM2 | |
| SCHEMBL6891672 | 0.76 | GRM2 (0.54) | GRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | disclosed |