Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158529 | 0.91 | PIK3CA (0.77) | PIK3CAMTOR | |
| SCHEMBL6893543 | 0.90 | PIK3CA (0.76) | PIK3CAMTOR | |
| SCHEMBL10157713 | 0.89 | PIK3CA (0.77) | PIK3CAMTOR | |
| SCHEMBL10157510 | 0.88 | PIK3CA (0.77) | PIK3CAMTOR | |
| SCHEMBL10129862 | 0.87 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL6893528 | 0.87 | PIK3CA (0.76) | PIK3CAMTOR | |
| SCHEMBL10158214 | 0.86 | MTOR (0.77) | PIK3CAMTOR | |
| SCHEMBL10157753 | 0.83 | PIK3CA (0.75) | PIK3CAMTOR | |
| SCHEMBL6894839 | 0.82 | PIK3CA (0.55) | PIK3CAMTOR | |
| SCHEMBL10158245 | 0.80 | MTOR (0.75) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092198-A1 | 5-ALKYNYL-PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |