Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MB | P02144 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894661 | 1.00 | MAPT (0.66) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11970674 | 0.89 | MAPT (0.66) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29051547 | 0.89 | MAPT (0.66) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11970671 | 0.89 | MAPT (0.66) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7941711 | 0.88 | SMN1; SMN2 (0.64) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10944710 | 0.88 | SMN1; SMN2 (0.64) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7941715 | 0.88 | SMN1; SMN2 (0.64) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL23866718 | 0.87 | MAPT (0.64) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1881515 | 0.87 | MAPT (0.69) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2134110 | 0.87 | MAPT (0.69) | MAPTMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018462-A1 | QUINAZOLINONE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |