⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680131 | 0.79 | — | — | |
| SCHEMBL14023874 | 0.77 | — | — | |
| SCHEMBL7992247 | 0.77 | — | — | |
| SCHEMBL13079186 | 0.76 | — | — | |
| SCHEMBL12881982 | 0.76 | — | — | |
| SCHEMBL15043613 | 0.75 | MIF (0.51) | — | |
| SCHEMBL14684907 | 0.75 | MIF (0.48) | — | |
| SCHEMBL17113713 | 0.74 | — | — | |
| SCHEMBL21610413 | 0.74 | — | — | |
| SCHEMBL14022364 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553074-B1 | FUSED BENZENE DERIVATIVE AND USE | TAKEDA PHARMACEUTICAL (JP) | 2014-06-18 | — | — | EP | disclosed |
| US-20100286211-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2010-11-11 | — | — | US | disclosed |
| US-20100286211-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2010-11-11 | — | — | US | disclosed |
| EP-0907625-A4 | FLUOROUS REACTION AND SEPARATION SYSTEMS | UNIV PITTSBURGH (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6156896-A | Fluorous reaction and separation systems | UNIVERSITY OF PITTSBURGH (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0907625-A1 | FLUOROUS REACTION AND SEPARATION SYSTEMS | UNIVERSITY OF PITTSBURGH (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5859247-A | Fluorous reaction and separation systems | UNIVERSITY OF PITTSBURGH (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1998000376-A1 | FLUOROUS REACTION AND SEPARATION SYSTEMS | UNIVERSITY OF PITTSBURGH (US) | 1998-01-08 | — | — | WO | disclosed |
| WO-1991016316-A1 | PROCESS FOR PREPARING ISOXAZOLINES | BP CHEMICALS LIMITED (GB) | 1991-10-31 | — | — | WO | disclosed |
| EP-0453189-A1 | Process for preparing isoxazolines | von Oppolzer, Wolfgang Wilhelm R.E.J. (CH) | 1991-10-23 | — | — | EP | disclosed |