Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 4/20 | 0.42 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349680 | 1.00 | CSNK1E (0.47) | CSNK1EF2POLBLTA4HLAP3 | |
| SCHEMBL3355926 | 0.92 | CSNK1E (0.48) | CSNK1EF2LTA4HLAP3ANPEP | |
| SCHEMBL6890895 | 0.85 | CSNK1E (0.50) | CSNK1EF2LTA4HLAP3ANPEP | |
| SCHEMBL3347304 | 0.85 | CSNK1E (0.50) | CSNK1EF2LTA4HLAP3ANPEP | |
| SCHEMBL3349250 | 0.84 | DRD4 (0.53) | F2LTA4H | |
| SCHEMBL6890855 | 0.84 | DRD4 (0.53) | F2LTA4H | |
| SCHEMBL5930069 | 0.84 | CSNK1E (0.57) | CSNK1EF2LAP3ANPEPRNPEP | |
| SCHEMBL6892294 | 0.83 | F2 (0.42) | CSNK1EF2LAP3ANPEPRNPEP | |
| SCHEMBL3354442 | 0.83 | F2 (0.42) | CSNK1EF2LAP3ANPEPRNPEP | |
| SCHEMBL14627960 | 0.83 | CSNK1E (0.53) | CSNK1EF2LAP3ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |