Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 3/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358249 | 1.00 | CSNK1E (0.51) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL7300383 | 0.92 | CSNK1E (0.54) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL1286637 | 0.90 | CSNK1E (0.51) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL1286638 | 0.90 | CSNK1E (0.51) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL1057036 | 0.90 | CSNK1E (0.51) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| Hydrochloric Acid SCHEMBL7310009 | 0.90 | CSNK1E (0.53) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| Hydrochloric Acid SCHEMBL5223863 | 0.89 | CSNK1E (0.50) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| Hydrochloric Acid SCHEMBL8734228 | 0.89 | CSNK1E (0.50) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL4047873 | 0.86 | BCHE (0.48) | CSNK1ESLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL3355611 | 0.85 | CSNK1E (0.56) | CSNK1ESLC6A2TAAR1MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |