Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13026107 | 0.91 | HTR2A (0.32) | HTR2A | |
| SCHEMBL2604709 | 0.89 | CYP2C9 (0.38) | HTR2ACYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL3274912 | 0.89 | CYP2C9 (0.38) | HTR2ACYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL30665195 | 0.89 | CYP2C9 (0.38) | HTR2ACYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL18134228 | 0.89 | CYP2C9 (0.38) | HTR2ACYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL12733782 | 0.89 | CYP2C9 (0.38) | HTR2ACYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9631433 | 0.88 | CYP2C9 (0.37) | HTR2ACYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9631426 | 0.88 | CYP2C9 (0.37) | HTR2ACYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL17369484 | 0.87 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL6660766 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081123-B1 | 2,3-Difluorophenyl derivative having negative dielectric anisotropy, liquid crystal composition, and liquid crystal display device | CHISSO CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6548126-B1 | Reduced electric power consumption and decreased leakage of electromagnetic waves | CHISSO CORPORATION (JP) | 2003-04-15 | — | — | US | disclosed |
| EP-1081123-A2 | 2,3-Difluorophenyl derivative having negative dielectric anisotropy, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2001-03-07 | — | — | EP | disclosed |