Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.34 |
| ▸ | CTSD | P07339 | 15/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377720 | 0.87 | BACE1 (0.34) | BACE1CTSDADRB1MAOB | |
| SCHEMBL5930180 | 0.82 | HPGD (0.39) | — | |
| SCHEMBL5930175 | 0.82 | HPGD (0.39) | — | |
| SCHEMBL5369028 | 0.81 | BACE1 (0.40) | BACE1CTSD | |
| SCHEMBL5447147 | 0.80 | BACE1 (0.38) | BACE1CTSD | |
| SCHEMBL5381670 | 0.77 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL5387700 | 0.77 | BACE1 (0.52) | BACE1CTSDADRB1 | |
| SCHEMBL5389034 | 0.77 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL5387696 | 0.77 | BACE1 (0.52) | BACE1CTSDADRB1 | |
| SCHEMBL14860346 | 0.75 | MAOB (0.33) | BACE1CTSDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |