⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035873 | 0.79 | — | — | |
| SCHEMBL2735586 | 0.78 | TDP1 (0.56) | — | |
| SCHEMBL28642552 | 0.77 | — | — | |
| SCHEMBL4683201 | 0.75 | — | — | |
| SCHEMBL23515495 | 0.73 | — | — | |
| SCHEMBL4683198 | 0.73 | — | — | |
| SCHEMBL18929522 | 0.73 | — | — | |
| SCHEMBL6898302 | 0.73 | — | — | |
| SCHEMBL93369 | 0.72 | — | — | |
| SCHEMBL42679 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110729-A1 | Primary N-hydroxylamines | NIH | 2004-06-10 | — | — | US | claimed |
| US-6455589-B1 | AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-24 | — | — | US | claimed |
| WO-2001030979-A1 | PRIMARY N-HYDROXYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-05-03 | — | — | WO | claimed |
| US-20160355577-A1 | METHODS AND COMPOSITIONS FOR TARGETING POLYUBIQUITIN | GENENTECH, INC. (US) | 2016-12-08 | — | — | US | disclosed |
| US-9365642-B2 | Methods and compositions for targeting polyubiquitin | GENENTECH, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160009791-A1 | METHODS AND COMPOSITIONS FOR TARGETING POLYUBIQUITIN | GENENTECH, INC. (US) | 2016-01-14 | — | — | US | disclosed |
| US-8426643-B2 | Synthesis of cyclohexane derivatives useful as sensates in consumer products | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-23 | — | — | US | disclosed |
| EP-2057189-B1 | ACYLATED EXENDIN-4 COMPOUNDS | NOVO NORDISK AS (DK) | 2013-03-06 | — | — | EP | disclosed |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-03-25 | — | — | US | disclosed |
| US-6455589-B1 | AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-24 | — | — | US | disclosed |
| WO-2001030979-A1 | PRIMARY N-HYDROXYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-05-03 | — | — | WO | disclosed |
| US-H53-H | Processes for producing herbicide intermediates | FMC CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |