Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 7/20 | 0.50 |
| ▸ | GALR1 | P47211 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247983 | 0.84 | USP2 (0.54) | GALR2GALR1USP2CYP1A2CYP3A4 | |
| SCHEMBL6895881 | 0.81 | GALR2 (0.49) | GALR2GALR1USP2CYP1A2CYP3A4 | |
| SCHEMBL8097371 | 0.79 | GALR2 (0.57) | GALR2GALR1PIK3CACTSLCTSB | |
| SCHEMBL8263323 | 0.78 | GALR2 (0.59) | GALR2GALR1CYP1A2CYP2C9CTSL | |
| SCHEMBL6788539 | 0.77 | GALR2 (0.54) | GALR2GALR1PIK3CAHTR2CHTR2A | |
| SCHEMBL3242747 | 0.77 | GALR2 (0.60) | GALR2GALR1PIK3CACTSLCTSB | |
| SCHEMBL3247288 | 0.76 | GALR1 (0.55) | GALR2GALR1LMNA | |
| SCHEMBL8256921 | 0.75 | GALR2 (0.56) | GALR2GALR1CTSLCTSBCTSS | |
| SCHEMBL8256924 | 0.75 | GALR2 (0.56) | GALR2GALR1LMNACTSLCTSB | |
| SCHEMBL6710674 | 0.75 | GALR2 (0.55) | GALR2GALR1CYP3A4CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127502-A1 | Use of GAL3 antagonist for treatment of depression | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127502-A1 | Use of GAL3 antagonist for treatment of depression | GALR3, GALR2, GALR1 | GALR2 2/4885GALR1 3/4885USP2 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.