SCHEMBL68965

SCHEMBL68965

CCOC(=O)C1CCCNC1C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
SLC6A2 P23975 3/20 0.37
SLC6A3 Q01959 3/20 0.37
SLC6A4 P31645 2/20 0.37
ALDH1A1 P00352 1/20 0.36
PPM1B O75688 1/20 0.36
PTPN1 P18031 1/20 0.36
PPP1CC P36873 1/20 0.36
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9087268 1.00 MEN1 (0.46) MEN1BLMKMT2AMAPTPKM
SCHEMBL26092526 0.89 MAPT (0.44) MAPTPKMALDH1A1PPM1BPTPN1
SCHEMBL7912832 0.83 MAPT (0.40) MEN1BLMKMT2AMAPTPKM
SCHEMBL16579360 0.83 MAPT (0.40) MEN1BLMKMT2AMAPTPKM
SCHEMBL16579394 0.83 MAPT (0.40) MEN1BLMKMT2AMAPTPKM
SCHEMBL2356808 0.83 MAPT (0.40) MEN1BLMKMT2AMAPTPKM
SCHEMBL7919683 0.83 MAPT (0.40) MEN1BLMKMT2AMAPTPKM
SCHEMBL19048799 0.83 MAPT (0.40) MEN1BLMKMT2AMAPTPKM
SCHEMBL21163728 0.80 MEN1 (0.36) MEN1BLMKMT2AMAPTPKM
SCHEMBL21901165 0.80 MAPT (0.38) MEN1BLMKMT2AMAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MEN1 4831/4885BLM 1873/4885KMT2A 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.