SCHEMBL6896564

SCHEMBL6896564

COC(=O)CCCCCCCCC1CO1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.48
LMNA P02545 2/20 0.46
EPHX2 P34913 4/20 0.45
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18530674 1.00 TSHR (0.50) TSHRALDH1A1LMNAEPHX2KMT2A
SCHEMBL18593567 0.98 TSHR (0.52) TSHRALDH1A1LMNAEPHX2KMT2A
SCHEMBL335984 0.92 TSHR (0.54) TSHRALDH1A1LMNAEPHX2KMT2A
SCHEMBL9430007 0.92 TSHR (0.54) TSHRALDH1A1LMNAEPHX2KMT2A
SCHEMBL10588095 0.89 TSHR (0.42) TSHRALDH1A1LMNAEPHX2KMT2A
SCHEMBL7373034 0.85 TSHR (0.50) TSHRALDH1A1LMNAEPHX2KMT2A
SCHEMBL414516 0.85 TSHR (0.50) TSHRALDH1A1LMNAEPHX2KMT2A
SCHEMBL17407789 0.84
SCHEMBL9665578 0.84
SCHEMBL19331659 0.84 TSHR (0.41) TSHRALDH1A1LMNAEPHX2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024787-A Method for catalyzing ring-opening polymerization of epsilon-caprolactone by using [ OSSO ] type complex 河北工业大学 2021-06-25 CN claimed
US-3956247-A Halogenation of EPDM in solution in the presence of epoxide and, optionally, poly(alkylene ether) glycol UNIROYAL INC. (US) 1976-05-11 US claimed
CN-113024787-A Method for catalyzing ring-opening polymerization of epsilon-caprolactone by using [ OSSO ] type complex 河北工业大学 2021-06-25 CN disclosed
US-20170349828-A1 POLYMERIZABLE COMPOSITION, FILM, AND HALF MIRROR FOR DISPLAYING PROJECTION IMAGE FUJIFILM CORPORATION (JP) 2017-12-07 US disclosed
US-20160108315-A1 OPTICALLY ANISOTROPIC LAYER, METHOD FOR PRODUCING THE OPTICALLY ANISOTROPIC LAYER, A LAMINATE, POLARIZING PLATE, DISPLAY DEVICE, LIQUID CRYSTAL COMPOUND, METHOD FOR PRODUCING THE LIQUID CRYSTAL COMPOUND, AND CARBOXYLIC ACID COMPOUND FUJIFILM CORPORATION (JP) 2016-04-21 US disclosed
EP-0699079-B1 BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES COMPRISING GENETIC MATERIALS DOW CHEMICAL CO (US) 2004-09-29 EP disclosed
US-6312679-B1 Dense star polymer conjugates as dyes THE DOW CHEMICAL COMPANY 2001-11-06 US disclosed
US-6177414-B1 POLYMAMINOAMIDE DENDRIMER STAR POLYMER CARRYING SALICYLIC ACID MOIETIES; DRUG DELIVERY THE DOW CHEMICAL COMPANY 2001-01-23 US disclosed
US-5714166-A Bioactive and/or targeted dendrimer conjugates THE DOW CHEMICAL COMPANY (US) 1998-02-03 US disclosed
EP-0763015-A1 SYSTEMATIC MODULAR PRODUCTION OF AMINIMIDE- AND OXAZOLONE- BASED MOLECULES HAVING AT LEAST TWO STRUCTURAL DIVERSITY ELEMENTS ARQULE, INC. (US) 1997-03-19 EP disclosed
US-5527524-A AGRICULTURAL, PHARMACEUTICAL, DRUG DELIVERY THE DOW CHEMICAL COMPANY (US) 1996-06-18 US disclosed
WO-1995032184-A1 SYSTEMATIC MODULAR PRODUCTION OF AMINIMIDE- AND OXAZOLONE- BASED MOLECULES HAVING AT LEAST TWO STRUCTURAL DIVERSITY ELEMENTS ARQULE, INC. (US) 1995-11-30 WO disclosed
US-5338532-A Star polymer as carrier for drugs, agricultural compounds THE DOW CHEMICAL COMPANY (US) 1994-08-16 US disclosed
US-3956247-A Halogenation of EPDM in solution in the presence of epoxide and, optionally, poly(alkylene ether) glycol UNIROYAL INC. (US) 1976-05-11 US disclosed