Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896440 | 0.87 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL6896911 | 0.86 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL10160331 | 0.83 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL10196544 | 0.78 | PIK3CA (0.64) | PIK3CAMTOR | |
| SCHEMBL503388 | 0.77 | PIK3CA (0.63) | PIK3CAMTOR | |
| SCHEMBL6896685 | 0.77 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL16573531 | 0.74 | PIK3CA (0.78) | PIK3CAMTOR | |
| SCHEMBL19241754 | 0.74 | PIK3CA (0.74) | PIK3CAMTOR | |
| SCHEMBL6894302 | 0.74 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL6896689 | 0.74 | PIK3CA (1.00) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528910-B1 | 5-Alkynyl pyrimidines ahd their use as kinase inhibitors. | BOEHRINGER INGELHEIM INT (DE) | 2015-03-18 | — | — | EP | disclosed |
| WO-2011092197-A1 | 5-ALKYNYL PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |