Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674781 | 0.92 | PHGDH (0.38) | PHGDHCYP3A4CYP2C19MEN1PKM | |
| SCHEMBL6676875 | 0.91 | PHGDH (0.42) | PHGDHCYP3A4CYP2C19MEN1PKM | |
| SCHEMBL6675122 | 0.91 | CYP3A4 (0.43) | PHGDHCYP3A4CYP2C19LMNAHSD17B10 | |
| SCHEMBL6675236 | 0.90 | CYP3A4 (0.32) | PHGDHCYP3A4CYP2C19LMNAHSD17B10 | |
| SCHEMBL6687937 | 0.89 | PHGDH (0.36) | PHGDHCYP3A4CYP2C19MEN1PKM | |
| SCHEMBL6675980 | 0.88 | PHGDH (0.41) | PHGDHCYP3A4CYP2C19MEN1PKM | |
| SCHEMBL6674652 | 0.85 | KMT2A (0.46) | MEN1KMT2A | |
| SCHEMBL6677879 | 0.84 | PHGDH (0.38) | PHGDHCYP3A4CYP2C19MEN1PKM | |
| SCHEMBL6675867 | 0.83 | PHGDH (0.39) | PHGDHCYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL6678312 | 0.83 | PHGDH (0.42) | PHGDHCYP3A4CYP2C19KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683184-B2 | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2004-01-27 | — | — | US | disclosed |