Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617231 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL290418 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL3404642 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL4417054 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL1300017 | 1.00 | — | — | |
| SCHEMBL3404645 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL1379861 | 1.00 | — | — | |
| SCHEMBL6055452 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL17851300 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL6897019 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |