SCHEMBL6897262

SCHEMBL6897262

CC(=O)OC(CC[SiH3])OC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM1 P11229 1/20 0.37
TBXA2R P21731 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
GALR3 O60755 1/20 0.35
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
ALOX15 P16050 1/20 0.33
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
HRH1 P35367 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6895761 0.86 TSHR (0.39) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10782810 0.84 TSHR (0.50) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL190306 0.82 TSHR (0.43) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL2230506 0.79 TSHR (0.46) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL6889383 0.79 TSHR (0.46) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10786488 0.77 TSHR (0.43) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL204649 0.75 TSHR (0.42) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL27640082 0.75 TSHR (0.42) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL29563402 0.74 TSHR (0.33) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL17014686 0.73 TSHR (0.40) TSHRCHRM2CHRM4CHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1098926-B1 CROSS-LINKABLE HYPERBRANCHED POLYMERS, METHOD FOR THE PRODUCTION AND USE OF THE SAME BAYER MATERIALSCIENCE AG (DE) 2004-03-03 EP disclosed
EP-1098926-A1 CROSS-LINKABLE HYPERBRANCHED POLYMERS, METHOD FOR THE PRODUCTION AND USE OF THE SAME Bayer Aktiengesellschaft (DE) 2001-05-16 EP disclosed
WO-2000002954-A1 CROSS-LINKABLE HYPERBRANCHED POLYMERS, METHOD FOR THE PRODUCTION AND USE OF THE SAME BAYER AKTIENGESELLSCHAFT (DE) 2000-01-20 WO disclosed