⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL28930006 | 0.80 | — | — | |
| Hydrazine SCHEMBL5815677 | 0.80 | — | — | |
| Hypochlorous Acid SCHEMBL7226959 | 0.80 | — | — | |
| Hydroxyamine SCHEMBL3273025 | 0.78 | — | — | |
| Hypochlorous Acid SCHEMBL15644 | 0.78 | — | — | |
| Hypochlorous Acid SCHEMBL482943 | 0.78 | — | — | |
| Hydroxyamine SCHEMBL1248 | 0.78 | — | — | |
| SCHEMBL30922366 | 0.78 | — | — | |
| Hydroxyamine SCHEMBL15869353 | 0.78 | — | — | |
| Hypochlorous Acid SCHEMBL28907544 | 0.78 | TSHR (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022406-A | PROCESSING FOUNDRY DUST, AND IN PARTICULAR DUST FROM ELECTRICAL STEELWORKS, PREPARING ZINC FERRITE | RECUPAC (FR) | 2000-02-08 | — | — | US | claimed |
| US-11807659-B2 | TGR5 modulators and methods of use thereof | INTERCEPT PHARMACEUTICALS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| WO-2023099201-A1 | A PRINTING METHOD FOR TIME TEMPERATURE INDICATORS | AGFA-GEVAERT NV (BE) | 2023-06-08 | — | — | WO | disclosed |
| EP-4190869-A1 | A PRINTING METHOD FOR TIME TEMPERATURE INDICATORS | AGFA-GEVAERT NV (BE) | 2023-06-07 | — | — | EP | disclosed |
| US-20230159504-A1 | 7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) | VERTEX PHARMACEUTICALS INCORPORATED | 2023-05-25 | — | — | US | disclosed |
| EP-4126819-A1 | 7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD) | Vertex Pharmaceuticals Incorporated (US) | 2023-02-08 | — | — | EP | disclosed |
| US-11345721-B2 | TGR5 modulators and methods of use thereof | INTERCEPT PHARMACEUTICALS, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| WO-2021203028-A1 | 7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD) | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-10-07 | — | — | WO | disclosed |
| US-20210122779-A1 | TGR5 MODULATORS AND METHODS OF USE THEREOF | INTERCEPT PHARMACEUTICALS, INC. | 2021-04-29 | — | — | US | disclosed |
| EP-3310801-B1 | TGR5 MODULATORS AND METHODS OF USE THEREOF | INTERCEPT PHARMACEUTICALS INC (US) | 2021-04-07 | — | — | EP | disclosed |
| US-4639477-A | AZO DYES | CIBA-GEIGY CORPORATION (US) | 1987-01-27 | — | — | US | disclosed |
| EP-0166151-A1 | Novel extractants and method for the recovery of palladium | AlliedSignal Inc. (US) | 1986-01-02 | — | — | EP | disclosed |
| EP-0036170-B1 | PROCESS FOR PREPARING SYNTHETIC RUBBER LATICES, THEIR USE AS RAW MATERIALS IN THE PREPARATION OF PRESSURE-SENSITIVE ADHESIVES, AND PRESSURE-SENSITIVE ADHESIVES | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| US-4445959-A | Process for the production of synthetic rubber latices, their use as a starting material in the production of pressure-sensitive adhesives and pressure-sensitive adhesives | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-01 | — | — | US | disclosed |
| US-4416893-A | Substituted 1,2,5-oxadiazole-2-oxides in human cardiovascular system disease | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-11-22 | — | — | US | disclosed |
| EP-0036170-A1 | Process for preparing synthetic rubber latices, their use as raw materials in the preparation of pressure-sensitive adhesives, and pressure-sensitive adhesives | BAYER AG (DE) | 1981-09-23 | — | — | EP | disclosed |
| US-4232113-A | P-PHENYLENEDIAMINE COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4180505-A | Novel steroidspirooxazolidines and process for their preparation | Richter Gedeon Vegyeszet, Gyar RT (HU) | 1979-12-25 | — | — | US | disclosed |
| US-3969421-A | MULTISTAGE, OXIDATION OF DIETHYLBENZENE | LABOFINA S.A. (BE) | 1976-07-13 | — | — | US | disclosed |
| US-3933803-A | ANTIBACTERIAL, ANTIMITOTIC, ANTIMYCOTIC | INSTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-01-20 | — | — | US | disclosed |