⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27509840 | 0.71 | — | — | |
| SCHEMBL9726152 | 0.69 | — | — | |
| SCHEMBL13562756 | 0.67 | — | — | |
| SCHEMBL22115 | 0.65 | — | — | |
| SCHEMBL15512819 | 0.65 | — | — | |
| SCHEMBL30955625 | 0.65 | — | — | |
| SCHEMBL2768911 | 0.65 | — | — | |
| SCHEMBL4929766 | 0.65 | — | — | |
| SCHEMBL14221321 | 0.64 | — | — | |
| Benzene SCHEMBL8002838 | 0.63 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103857644-A | Method for the synthesis of 18F-labelled biomolecules | GE HEALTHCARE LTD | 2014-06-11 | — | — | CN | disclosed |
| CN-101142189-A | 2-pyridine derivatives as inhibitors of neutrophile elastase | ASTRAZENECA AB (SE) | 2008-03-12 | — | — | CN | disclosed |
| EP-1487444-A1 | USE OF PYRIDYL AMIDES AS INHIBITORS OF ANGIOGENESIS | Fujisawa Deutschland GmbH (DE) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080054-A1 | USE OF PYRIDYL AMIDES AS INHIBITORS OF ANGIOGENESIS | FUJISAWA DEUTSCHLAND GMBH (DE) | 2003-10-02 | — | — | WO | disclosed |
| CN-86100228-A | The preparation method of polycyclic salts | — | 1986-10-29 | — | — | CN | disclosed |