SCHEMBL6898391

SCHEMBL6898391

C=C(C)C(=O)OCCC[Si](OC)(OC)OC.CC=C(C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.38
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL4313343 0.90 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28200351 0.88 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
Propene SCHEMBL28052131 0.88 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15276 0.88 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5446210 0.88 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL30426756 0.88 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
Hydrogen Sulfide SCHEMBL329768 0.86 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23437 0.86 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29962797 0.86 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL17201482 0.86 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1114716-A1 Moulded articles having a high filler content and preparation process thereof TELMA GUZZINI S.r.l. (IT) 2001-07-11 EP claimed
WO-2014202484-A1 DENTAL PROSTHESES MEDLIFE S.R.L. (IT) 2014-12-24 WO disclosed
EP-1114716-B1 Moulded articles having a high filler content and preparation process thereof TELMA GUZZINI S R L (IT) 2004-07-21 EP disclosed
EP-1114716-A1 Moulded articles having a high filler content and preparation process thereof TELMA GUZZINI S.r.l. (IT) 2001-07-11 EP disclosed
US-5385973-A Mixing liquid monomers, finely ground fillers, silanizing agent, hydrolysis catalyst consisting of ammonium salt of acids VEDRIL S.P.A. (IT) 1995-01-31 US disclosed
EP-0321193-B1 Process for preparing flowable, stable and hardenable suspensions, and thus-obtained compositions ATOCHEM ELF ITALIA (IT) 1994-04-20 EP disclosed
EP-0321193-A2 Process for preparing flowable, stable and hardenable suspensions, and thus-obtained compositions ELF ATOCHEM ITALIA S.r.l. (IT) 1989-06-21 EP disclosed