Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894765 | 0.92 | MEN1 (0.46) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6897498 | 0.90 | MCHR1 (0.51) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6900622 | 0.84 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6894761 | 0.81 | MCHR1 (0.51) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6892155 | 0.77 | MCHR1 (0.55) | ALDH1A1MCHR1RAB9A | |
| SCHEMBL6898470 | 0.76 | MEN1 (0.48) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6604498 | 0.75 | MCHR1 (0.55) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6899460 | 0.75 | MCHR1 (0.62) | ALDH1A1MCHR1RAB9A | |
| SCHEMBL6900615 | 0.73 | MCHR1 (0.61) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6927024 | 0.73 | MCHR1 (0.66) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100485-A4 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-06-09 | — | — | EP | claimed |
| JP-2002521436-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100485-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006146-A9 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2000-08-03 | — | — | WO | claimed |
| WO-2000006146-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| WO-2000006146-A9 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2000-08-03 | — | — | WO | disclosed |