⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420043 | 0.79 | — | — | |
| SCHEMBL23279351 | 0.62 | — | — | |
| SCHEMBL22417489 | 0.54 | — | — | |
| SCHEMBL10356905 | 0.51 | — | — | |
| SCHEMBL9881076 | 0.50 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL10207141 | 0.49 | — | — | |
| SCHEMBL20224242 | 0.49 | — | — | |
| SCHEMBL13771602 | 0.49 | — | — | |
| SCHEMBL11582002 | 0.48 | — | — | |
| SCHEMBL9965147 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011030068-A1 | USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR THE APPLICATION THEREOF AS A MEDICAMENT FOR THE TREATMENT OF PARKINSON'S DISEASE | LABORATOIRES FOURNIER SA (FR) | 2011-03-17 | — | — | WO | disclosed |