Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690670 | 1.00 | TYR (0.37) | TYRDAOKDM4E | |
| SCHEMBL6506819 | 0.96 | TYR (0.37) | TYRDAOKDM4E | |
| SCHEMBL6708527 | 0.92 | TYR (0.39) | TYRDAOKDM4E | |
| SCHEMBL6703806 | 0.90 | TYR (0.45) | TYRDAOKDM4E | |
| SCHEMBL6707601 | 0.88 | — | — | |
| SCHEMBL6899754 | 0.86 | — | — | |
| SCHEMBL6505374 | 0.85 | TYR (0.45) | TYRDAOKDM4E | |
| SCHEMBL6505404 | 0.83 | — | — | |
| SCHEMBL3279862 | 0.83 | TYR (0.39) | TYRDAOKDM4E | |
| SCHEMBL6258441 | 0.83 | DAO (0.40) | TYRDAOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673780-B2 | SUCH AS 4-(4-(3-HYDROXY-3-METHYL-BUTANE-1-SULFINYLMETHYL)-PHENYLMETHANESULFINYL)-2 -METHYL-BUTAN1-OL FOR TREATING AND PREVENTING CARDIOVASCULAR DISEASES, DYSLIPIDEMIAS, DYSPROTEINEMIAS, AND GLUCOSE METABOLISM DISORDERS | ESPERION THERAPEUTICS, INC. | 2004-01-06 | — | — | US | disclosed |