Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 2/20 | 0.36 |
| ▸ | PGK2 | P07205 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334769 | 0.83 | — | — | |
| SCHEMBL5491040 | 0.80 | TDP1 (0.39) | TDP1FDPSBLMPGK1PGK2 | |
| SCHEMBL2991822 | 0.80 | — | — | |
| SCHEMBL23062646 | 0.78 | TDP1 (0.37) | TDP1FDPSBLMPGK1PGK2 | |
| SCHEMBL2699115 | 0.78 | TDP1 (0.37) | TDP1FDPSBLMPGK1PGK2 | |
| SCHEMBL12694704 | 0.75 | — | — | |
| SCHEMBL2134670 | 0.75 | — | — | |
| Ethylene SCHEMBL29094194 | 0.75 | TDP1 (0.35) | TDP1FDPSBLMPGK1PGK2 | |
| SCHEMBL27592565 | 0.75 | TDP1 (0.35) | TDP1FDPSBLMPGK1PGK2 | |
| SCHEMBL588728 | 0.75 | TDP1 (0.35) | TDP1FDPSBLMPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965242-A | Synthesis method of novel difluoromethylene phosphate salt, and application of novel difluoromethylene phosphate salt | SHANGHAI INST ORGANIC CHEM | 2014-08-06 | — | — | CN | disclosed |
| CN-103965242-A | Synthesis method of novel difluoromethylene phosphate salt, and application of novel difluoromethylene phosphate salt | SHANGHAI INST ORGANIC CHEM | 2014-08-06 | — | — | CN | disclosed |
| US-20040009123-A1 | Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2004-01-15 | — | — | US | disclosed |
| US-20040006131-A1 | Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2004-01-08 | — | — | US | disclosed |
| US-6624151-B1 | Concerns the uses of said compounds as selective inhibitors of T gamma 9 delta 2 lymphocytes, their uses, for therapeutic purposes. | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2003-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006131-A1 | Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes | CD4, IL2RA, CD74 | TDP1 2384/4885FDPS 2429/4885BLM 4823/4885 |
| US-20040009123-A1 | Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes | CD4, IL2RA, CD74 | TDP1 2384/4885FDPS 2429/4885BLM 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.