Thiourea

Thiourea

SCHEMBL6900327

N.NC(N)=S

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL2514866 1.00
Thiourea SCHEMBL7719534 0.94
Thiourea SCHEMBL31425705 0.94
Thiourea SCHEMBL850383 0.93
Thiourea SCHEMBL30536984 0.93
Thiourea SCHEMBL30536978 0.93
Thiourea SCHEMBL1008 0.93
Thiourea SCHEMBL2766859 0.86
Thiourea SCHEMBL156287 0.86
Thiourea SCHEMBL619321 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112724832-A Water-soluble diesel modified environment-friendly asphalt separant 安徽省路兴建设项目管理有限公司 2021-04-30 CN claimed
CN-112264091-A Axial chiral styrene tertiary amine thiourea catalyst and preparation method and application thereof 江苏师范大学 2021-01-26 CN claimed
CN-105753726-B Preparation method for asymmetrically synthesizing pregabalin 深圳市华先医药科技有限公司 2020-11-10 CN claimed
CN-110467622-A A kind of novel kojic acid benzofuran compound and preparation method thereof CHENGDU ORGANIC CHEM CO LTD CAS 2019-11-19 CN claimed
CN-109867955-A A kind of spherical nanometer MoS2/ hydroxy silicate/bismaleimide resin composite material and preparation method thereof 西安文理学院 2019-06-11 CN claimed
CN-106008242-A Asymmetric alcoholysis catalyzed by chiral thiourea amine salt 惠州市莱佛士制药技术有限公司 2016-10-12 CN claimed
CN-105964297-A Preparation method for immobilized catalyst for synthesizing oximidobenzofuran derivative 浙江师范大学 2016-09-28 CN claimed
CN-105753726-A Preparation method for asymmetrical synthesis of pregabalin 深圳市华先医药科技有限公司 2016-07-13 CN claimed
CN-101508617-A Process for preparing large-particle long-acting ammonium thiourea LIAONING HUAJIN CHEMICALS GROU (CN) 2009-08-19 CN claimed
US-20250043323-A1 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) 2025-02-06 US disclosed
US-20240327884-A1 ATP-PRT VARIANT WITH REDUCED FEEDBACK INHIBITION BY HISTIDINE, AND HISTIDINE-PRODUCING STRAIN EXPRESSING SAME DAESANG CORPORATION (KR) 2024-10-03 US disclosed
EP-4433602-A1 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) 2024-09-25 EP disclosed
CN-118006520-A L-amino acid-producing E.coli or Corynebacterium glutamicum mutant strain and method for producing L-amino acid using the same 大象株式会社 2024-05-10 CN disclosed
US-20240068000-A1 ATP-PRT VARIANT WITH REDUCED FEEDBACK INHIBITION BY HISTIDINE, AND HISTIDINE-PRODUCING STRAIN EXPRESSING SAME DAESANG CORPORATION (KR) 2024-02-29 US disclosed
EP-1133493-A1 OXAZOLIDINONE ANTIBACTERIAL AGENTS HAVING A THIOCARBONYL FUNCTIONALITY PHARMACIA &amp; UPJOHN COMPANY (US) 2001-09-19 EP disclosed
EP-1124920-A1 CYCLIC THIOUREA ADDITIVES FOR LUBRICANTS UNIROYAL CHEMICAL COMPANY, Inc. (US) 2001-08-22 EP disclosed
WO-2000053703-A1 CYCLIC THIOUREA ADDITIVES FOR LUBRICANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-09-14 WO disclosed
WO-2000032599-A1 OXAZOLIDINONE ANTIBACTERIAL AGENTS HAVING A THIOCARBONYL FUNCTIONALITY PHARMACIA & UPJOHN COMPANY (US) 2000-06-08 WO disclosed
US-5935913-A EXTREME PRESSURE LUBRICANTS; ASHLESS AND NONPHOSPHORUS, ANTIWEAR, ANTIFATIGUE UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-08-10 US disclosed
EP-0013462-A1 Dithiocarbamate/sulfonium salt corrosion inhibitor composition and its use in acidic cleaning solutions Amchem Products, Inc. a Corporation organised under the Laws of the State of Delaware United States of America (US) 1980-07-23 EP disclosed