Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 4/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 3/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739177 | 0.79 | CTSA (0.43) | GABBR2GABBR1 | |
| SCHEMBL11663589 | 0.77 | METAP1 (0.32) | GABBR2GABBR1LAP3METAP1ANPEP | |
| Hydrochloric Acid SCHEMBL27411734 | 0.77 | CTSA (0.42) | GABBR2GABBR1 | |
| SCHEMBL10981524 | 0.76 | METAP1 (0.38) | GABBR2GABBR1GABRR1LAP3METAP1 | |
| SCHEMBL21219389 | 0.70 | TSHR (0.58) | — | |
| SCHEMBL1080348 | 0.69 | CTSA (0.36) | — | |
| SCHEMBL15598402 | 0.68 | CTSA (0.39) | — | |
| SCHEMBL7717615 | 0.67 | CTSA (0.35) | LAP3 | |
| SCHEMBL8056927 | 0.67 | — | — | |
| SCHEMBL28532170 | 0.67 | TSHR (0.38) | LAP3METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111194329-A | Rigid polyurethane foams containing reactive flame retardants | 爱思乐-艾博美国有限公司 | 2020-05-22 | — | — | CN | claimed |
| JP-2004501255-A | — | — | 2004-01-15 | — | — | JP | claimed |
| EP-1297062-A1 | FLAME RETARDANT BLEND FOR INTUMESCENT FLEXIBLE POLYURETHANE FOAM | Akzo Nobel N.V. (NL) | 2003-04-02 | — | — | EP | claimed |
| WO-2001098401-A1 | FLAME RETARDANT BLEND FOR INTUMESCENT FLEXIBLE POLYURETHANE FOAM | AKZO NOBEL N.V. (NL) | 2001-12-27 | — | — | WO | claimed |
| CN-116425938-A | Flame-retardant polyurethane soft foam with excellent mechanical properties and preparation method thereof | 江苏米尔化工科技有限公司 | 2023-07-14 | — | — | CN | disclosed |