⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47224 | 0.62 | — | — | |
| SCHEMBL15382251 | 0.62 | — | — | |
| SCHEMBL426923 | 0.62 | — | — | |
| Potassium SCHEMBL31174422 | 0.61 | — | — | |
| SCHEMBL29111914 | 0.61 | — | — | |
| SCHEMBL31686392 | 0.61 | — | — | |
| SCHEMBL11203688 | 0.60 | — | — | |
| SCHEMBL19065228 | 0.60 | — | — | |
| SCHEMBL1686922 | 0.57 | — | — | |
| SCHEMBL19875447 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127992-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1993-01-13 | — | — | EP | claimed |
| US-4855420-A | Cephalosporin derivatives | ICI PHARMA (FR) | 1989-08-08 | — | — | US | claimed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | claimed |
| EP-0127992-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1984-12-12 | — | — | EP | claimed |
| US-4145540-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-20 | — | — | US | claimed |
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-7915267-B2 | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20090137603-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1953148-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-0127992-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1993-01-13 | — | — | EP | disclosed |
| US-4855420-A | Cephalosporin derivatives | ICI PHARMA (FR) | 1989-08-08 | — | — | US | disclosed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | disclosed |
| EP-0127992-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1984-12-12 | — | — | EP | disclosed |
| EP-0015240-A1 | Azacyclyl (thio) ureidoacetyl compounds and their preparation | CIBA-GEIGY AG (CH) | 1980-09-03 | — | — | EP | disclosed |
| US-4187374-A | 7-(β-Aminoacylamino)-3-substituted-3-cephem-4-carboxylic acid derivatives and preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-05 | — | — | US | disclosed |
| US-4094872-A | 7-(β-Aminoacylamino)-3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-06-13 | — | — | US | disclosed |