Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 8/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.61 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.61 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900967 | 0.89 | MTOR (0.77) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6900006 | 0.77 | MTOR (0.91) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6900750 | 0.77 | MTOR (0.78) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913668 | 0.76 | MTOR (0.80) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913379 | 0.76 | MTOR (1.00) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899737 | 0.76 | MTOR (0.81) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6900260 | 0.74 | MTOR (0.77) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6900930 | 0.74 | MTOR (0.88) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL23309801 | 0.74 | MTOR (0.78) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL23309806 | 0.74 | MTOR (0.78) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |