SCHEMBL6900921

SCHEMBL6900921

C=C(OC1CC(C)(C)NC(C)(C)C1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
ALOX15 P16050 1/20 0.36
POLB P06746 2/20 0.36
EZH2 Q15910 3/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.34
KMT2A Q03164 2/20 0.33
PKM P14618 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5549633 0.84 GAA (0.47) GAAL3MBTL1ATMPOLBKMT2A
SCHEMBL27461056 0.81 GAA (0.56) GAAL3MBTL1ATMALOX15POLB
SCHEMBL11495138 0.80 GAA (0.59) GAAL3MBTL1ATMALOX15POLB
SCHEMBL11478663 0.79 GAA (0.53) GAAL3MBTL1ATMPOLBEZH2
SCHEMBL11846467 0.78 GAA (0.43) GAAL3MBTL1ATMALOX15POLB
SCHEMBL16702066 0.78 GAA (0.56) GAAL3MBTL1ATMPOLBEZH2
SCHEMBL674787 0.78 GAA (0.56) GAAL3MBTL1ATMPOLBEZH2
SCHEMBL134388 0.78 GAA (0.56) GAAL3MBTL1ATMPOLBEZH2
SCHEMBL107001 0.78 GAA (0.49) GAAL3MBTL1ATMPOLBEZH2
SCHEMBL8791145 0.77 GAA (0.51) GAAL3MBTL1ATMPOLBEZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1322701-B1 SCORCH-DELAYING COMPOSITION ATOFINA (FR) 2004-11-24 EP claimed
US-4141883-A Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives SANKYO COMPANY, LIMITED (JP) 1979-02-27 US disclosed
US-4075165-A 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed