Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6901216

CCCOP(=S)(S)OCCC.S.S.S.S

nearest known ligand 0.36

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.36
LPAR3 Q9UBY5 3/20 0.36
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL7967014 1.00 LPAR2 (0.36) LPAR2LPAR3MEN1KMT2ACYP3A4
Hydrogen Sulfide SCHEMBL6900857 1.00 LPAR2 (0.36) LPAR2LPAR3MEN1KMT2ACYP3A4
SCHEMBL482317 0.97 LPAR2 (0.37) LPAR2LPAR3MEN1KMT2ACYP3A4
Water SCHEMBL27918128 0.94 LPAR2 (0.36) LPAR2LPAR3MEN1KMT2ACYP3A4
SCHEMBL27451330 0.94 LPAR2 (0.36) LPAR2LPAR3MEN1KMT2ACYP3A4
SCHEMBL7007024 0.94 LPAR2 (0.36) LPAR2LPAR3MEN1KMT2ACYP3A4
Ammonia Solution, Strong SCHEMBL10929934 0.94 LPAR2 (0.36) LPAR2LPAR3MEN1KMT2ACYP3A4
Water SCHEMBL27456576 0.92 LPAR2 (0.34) LPAR2LPAR3MEN1KMT2A
Zinc Ion SCHEMBL2991140 0.92 LPAR2 (0.34) LPAR2LPAR3MEN1KMT2A
SCHEMBL10625338 0.89 TDP1 (0.35) LPAR2LPAR3MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945482-B1 Rubber composition for tire tread and pneumatic tire using same BRIDGESTONE CORP (JP) 2004-01-28 EP disclosed
US-6242522-B1 A DIENE BASED SYNTHETIC RUBBER OR NATURAL RUBBER BLEND CONTAINING BUTADIENE-STYRENE RUBBER, ALUMINUM HYDROXIDE POWDER, SILICA POWDER, CARBON BLACK; LOW FUEL CONSUMPTION AND WEAR RESISTANCE; IMPROVED GRIPPING IN WET AND COLD SITUATIONS BRIDGESTONE CORPORATION (JP) 2001-06-05 US disclosed
EP-0948029-A2 High pressure discharge lamp NGK INSULATORS, LTD. (JP) 1999-10-06 EP disclosed