Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741717 | 0.87 | MEN1 (0.54) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL6901859 | 0.83 | KMT2A (0.50) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL7393652 | 0.82 | MEN1 (0.76) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL379160 | 0.82 | MEN1 (0.76) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL3970912 | 0.82 | MEN1 (0.76) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL4814264 | 0.82 | MEN1 (0.76) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL894510 | 0.82 | MEN1 (0.60) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL3934434 | 0.81 | MEN1 (0.59) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL15011579 | 0.80 | MEN1 (0.73) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| Bicarbonate SCHEMBL4357688 | 0.80 | MEN1 (0.73) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |