Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SAT1 | P21673 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1543426 | 0.78 | CYP2C19 (0.71) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL2893263 | 0.78 | CYP2C19 (0.71) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL9300332 | 0.77 | — | — | |
| SCHEMBL9055069 | 0.76 | — | — | |
| SCHEMBL80292 | 0.74 | — | — | |
| SCHEMBL4527291 | 0.72 | — | — | |
| SCHEMBL12794871 | 0.72 | CYP2C19 (0.42) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| Iodide SCHEMBL7119508 | 0.71 | CYP2C19 (0.60) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL13859051 | 0.71 | CYP2C19 (0.60) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL11321305 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819432-B1 | ANTITUMOR AGENTS COMPRISING AS THE PRINCIPAL AGENT COMPOUNDS CONTAINING SILICON AND NITROGEN | JAPAN SCIENCE & TECH CORP (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-0819432-A1 | ANTITUMOR AGENTS COMPRISING AS THE PRINCIPAL AGENT COMPOUNDS CONTAINING SILICON AND NITROGEN | Japan Science and Technology Corporation (JP) | 1998-01-21 | — | — | EP | disclosed |