Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 12/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513661 | 0.88 | GRM2 (0.85) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1513664 | 0.88 | GRM2 (0.85) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3135252 | 0.87 | GRM2 (0.74) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3135263 | 0.87 | GRM2 (0.74) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1513224 | 0.86 | GRM2 (0.72) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1513227 | 0.86 | GRM2 (0.72) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1513654 | 0.86 | GRM2 (0.75) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1513478 | 0.86 | GRM2 (0.75) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1513460 | 0.86 | GRM2 (1.00) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1513475 | 0.86 | GRM2 (0.75) | GRM2KDM4EMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |