SCHEMBL6901760

SCHEMBL6901760

CCCCCCCCCCCCCCCCCC1(O[SiH3])OO1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634961 1.00 TSHR (0.38) TSHRTHRB
SCHEMBL7209591 0.98 TSHR (0.36) TSHRTHRB
SCHEMBL4076347 0.98 TSHR (0.36) TSHRTHRB
SCHEMBL27703237 0.98 TSHR (0.36) TSHRTHRB
SCHEMBL23211157 0.79 TSHR (0.36) TSHRTHRB
SCHEMBL28248015 0.79 TSHR (0.36) TSHRTHRB
SCHEMBL28456357 0.77 TSHR (0.35) TSHRTHRB
Decane SCHEMBL28281087 0.70 TSHR (0.57) TSHRTHRB
Octane SCHEMBL29116514 0.69 TSHR (0.67) TSHRTHRB
SCHEMBL9849172 0.67 TSHR (0.44) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699235-A METHOD FOR PRODUCING POLYETHER RUBBER 日本瑞翁株式会社 2018-10-23 CN disclosed
CN-105829397-B The manufacturing method of polyether rubber 日本瑞翁株式会社 2018-05-22 CN disclosed
EP-0787487-B1 Pharmaceutical granulates containing an intragranular disintegrant BEECHAM LAB SA (ES) 2004-12-22 EP disclosed
EP-0783889-B1 Pharmaceutical granulates containing an intragranular disintegrant BEECHAM LAB SA (ES) 2003-10-29 EP disclosed