Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.63 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901599 | 0.86 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL1673245 | 0.77 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1672116 | 0.77 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL6924951 | 0.75 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL11907843 | 0.71 | HCRTR1 (0.64) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL6924831 | 0.66 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671090 | 0.65 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL1673054 | 0.64 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671684 | 0.64 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL13736475 | 0.64 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050200-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-28 | — | — | WO | disclosed |