Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL6899432 | 1.00 | CYP3A4 (0.59) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL598265 | 0.98 | CYP3A4 (0.61) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL2456068 | 0.96 | CYP3A4 (0.59) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL3271728 | 0.96 | CYP3A4 (0.59) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| Ammonia Solution, Strong SCHEMBL10936576 | 0.96 | CYP3A4 (0.59) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| Zinc Ion SCHEMBL2986391 | 0.95 | CYP3A4 (0.58) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL29884106 | 0.93 | CYP3A4 (0.56) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL10824056 | 0.93 | CYP3A4 (0.61) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL10477521 | 0.91 | CYP3A4 (0.54) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL20310386 | 0.90 | CYP3A4 (0.53) | CYP3A4L3MBTL1TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945482-B1 | Rubber composition for tire tread and pneumatic tire using same | BRIDGESTONE CORP (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-6242522-B1 | A DIENE BASED SYNTHETIC RUBBER OR NATURAL RUBBER BLEND CONTAINING BUTADIENE-STYRENE RUBBER, ALUMINUM HYDROXIDE POWDER, SILICA POWDER, CARBON BLACK; LOW FUEL CONSUMPTION AND WEAR RESISTANCE; IMPROVED GRIPPING IN WET AND COLD SITUATIONS | BRIDGESTONE CORPORATION (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0948029-A2 | High pressure discharge lamp | NGK INSULATORS, LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |