Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053928 | 0.87 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2042044 | 0.85 | PDE10A (1.00) | PDE10A | |
| SCHEMBL17174593 | 0.85 | PDE10A (0.60) | PDE10A | |
| SCHEMBL14211455 | 0.82 | PDE10A (0.76) | PDE10A | |
| SCHEMBL6901436 | 0.78 | PDE10A (0.69) | PDE10A | |
| SCHEMBL2040621 | 0.76 | PDE10A (1.00) | PDE10A | |
| SCHEMBL259142 | 0.75 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2042016 | 0.74 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2043690 | 0.74 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2046158 | 0.72 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096589-B2 | Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors | H. LUNDBECK A/S (DK) | 2015-08-04 | — | — | US | disclosed |
| US-9096589-B2 | Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors | H. LUNDBECK A/S (DK) | 2015-08-04 | — | — | US | disclosed |
| EP-2513107-B1 | HETEROAROMATIC PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | LUNDBECK & CO AS H (DK) | 2014-07-30 | — | — | EP | disclosed |
| US-20120309714-A1 | Heteroaromatic Phenylimidazole derivatives as PDE10A enzyme inhibitors | H. LUNDBECK A/S (DK) | 2012-12-06 | — | — | US | disclosed |
| US-20120309714-A1 | Heteroaromatic Phenylimidazole derivatives as PDE10A enzyme inhibitors | H. LUNDBECK A/S (DK) | 2012-12-06 | — | — | US | disclosed |
| WO-2011072694-A1 | HETEROAROMATIC PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309714-A1 | Heteroaromatic Phenylimidazole derivatives as PDE10A enzyme inhibitors | PDE10A, PDE3B, PDE4A | PDE10A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.