SCHEMBL6902889

SCHEMBL6902889

O=C=NC(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.37
CYP2C9 P11712 3/20 0.35
CYP2C19 P33261 3/20 0.35
PTPN1 P18031 1/20 0.35
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
TSHR P16473 3/20 0.34
ALDH1A1 P00352 3/20 0.34
KCNN4 O15554 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP2D6 P10635 2/20 0.32
HTT P42858 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1140209 0.82 CYP1A2 (0.37) CYP1A2CYP2C9CYP2C19PTPN1MAPT
SCHEMBL22444493 0.78 KMT2A (0.41) CYP1A2CYP2C19PTPN1MAPTKMT2A
SCHEMBL129231 0.76 KCNN4 (0.36) CYP1A2CYP2C19PTPN1MAPTKMT2A
SCHEMBL3517726 0.76 KCNN4 (0.36) CYP1A2CYP2C19PTPN1MAPTKMT2A
SCHEMBL15413 0.76 KCNN4 (0.36) CYP1A2CYP2C19PTPN1MAPTKMT2A
SCHEMBL1149592 0.76 KCNN4 (0.36) CYP1A2CYP2C19PTPN1MAPTKMT2A
Water SCHEMBL10334361 0.74 KCNN4 (0.35) CYP1A2CYP2C19PTPN1MAPTKMT2A
Water SCHEMBL2069627 0.74 KCNN4 (0.35) CYP1A2CYP2C19PTPN1MAPTKMT2A
SCHEMBL8578358 0.74 KCNN4 (0.35) CYP1A2CYP2C19PTPN1MAPTKMT2A
SCHEMBL28448472 0.74 KCNN4 (0.35) CYP1A2CYP2C19PTPN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746562-B2 STABLE CROSSLINKED STRUCTURE AT ROOM TEMPERATURE, THEREBY HAVING RUBBER PLASTICITY, SUFFICIENT MELT FLOWABILITY AND REPEATED CROSSLINKING FORMATION AND DISSOCIATION THE YOKOHAMA RUBBER CO., LTD (JP) 2004-06-08 US disclosed
US-20040059060-A1 Thermo-reversible, crosslinkable elastomer and composition thereof CHINO KEISUKE (JP) 2004-03-25 US disclosed