Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443967 | 0.81 | BACE1 (0.44) | GAAKDM4EGLABACE1CYP1A2 | |
| SCHEMBL7563324 | 0.80 | KMT2A (0.59) | GAAKDM4EGLABACE1L3MBTL1 | |
| SCHEMBL15443962 | 0.79 | BACE1 (0.43) | GAAKDM4EGLABACE1CYP1A2 | |
| SCHEMBL13193768 | 0.79 | BACE1 (0.53) | GAAKDM4EGLABACE1CYP1A2 | |
| SCHEMBL70624 | 0.78 | GAA (0.67) | GAAKDM4EGLACYP1A2LMNA | |
| SCHEMBL6904018 | 0.77 | KDM4E (0.52) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL19189460 | 0.76 | BACE1 (0.41) | GAAKDM4EGLABACE1CYP1A2 | |
| SCHEMBL15431078 | 0.76 | BACE1 (0.50) | GAAKDM4EGLABACE1CYP1A2 | |
| SCHEMBL17277724 | 0.76 | BACE1 (0.50) | GAAKDM4EGLABACE1CYP1A2 | |
| SCHEMBL13193769 | 0.76 | BACE1 (0.41) | GAAKDM4EGLABACE1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696575-B2 | POLYTHIOPHENE-POLYPYRROLE BLOCK COPOLYMER; NERVOUS SYSTEM REGENERATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-02-24 | — | — | US | disclosed |
| US-20030066987-A1 | Biodegradable, electrically conducting polymer for tissue engineering applications | AXOGEN CORPORATION | 2003-04-10 | — | — | US | disclosed |