⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573273 | 0.72 | — | — | |
| SCHEMBL11147167 | 0.69 | — | — | |
| SCHEMBL6083962 | 0.69 | — | — | |
| SCHEMBL6478471 | 0.67 | — | — | |
| SCHEMBL15791946 | 0.67 | — | — | |
| SCHEMBL4602390 | 0.67 | — | — | |
| SCHEMBL27396010 | 0.67 | — | — | |
| SCHEMBL975089 | 0.67 | — | — | |
| SCHEMBL260946 | 0.67 | — | — | |
| SCHEMBL6085814 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833481-B2 | Catalytic dehydrative isomerization | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-12-21 | — | — | US | disclosed |
| US-20030109755-A1 | Process for producing 2-alkyl-2cyclopentenones | TAKASAGO INTERNATIONAL CORPORATION | 2003-06-12 | — | — | US | disclosed |
| EP-1316541-A1 | Process for producing 2-alkyl-2-cyclopentenones | Takasago International Corporation (JP) | 2003-06-04 | — | — | EP | disclosed |
| CN-1421429-A | Process for producing 2-alkyl-2-cyclopentenone | TAKASAGO PERFUMERY CO LTD (JP) | 2003-06-04 | — | — | CN | disclosed |
| US-5246930-A | Malaria | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |
| US-5225427-A | 10-substituted ether derivatives of dihydroartemisinin, process for their preparation and their use as antiprotozoal agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0456149-A1 | 9-Substituted compounds of 3 alpha, 11 alpha-Epoxy-3,4,5, 5a alpha,6,7,8,8a,9,11,11a-undecahydro-3 beta, 6 alpha, 9-trimethylfurano[3,4-j][1,2]-benzodioxepin, processes for their preparation and their use as antiprotozoal and antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-13 | — | — | EP | disclosed |
| EP-0362730-A1 | Artemisinin derivatives, processes for their preparation and their use as antiprotozoal agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | disclosed |