Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513390 | 0.89 | GRM2 (0.65) | GRM2SMN1; SMN2KDM4ENPSR1PRKAB2 | |
| SCHEMBL1513394 | 0.89 | GRM2 (0.65) | GRM2SMN1; SMN2KDM4ENPSR1PRKAB2 | |
| SCHEMBL3135252 | 0.88 | GRM2 (0.74) | GRM2FFAR1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3135263 | 0.88 | GRM2 (0.74) | GRM2FFAR1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3134492 | 0.88 | GRM2 (0.73) | GRM2SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL1513388 | 0.85 | GRM2 (0.67) | GRM2FFAR1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL1513391 | 0.85 | GRM2 (0.67) | GRM2FFAR1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL1513672 | 0.84 | GRM2 (0.74) | GRM2SMN1; SMN2KDM4ENPSR1DGAT1 | |
| SCHEMBL1513675 | 0.84 | GRM2 (0.74) | GRM2SMN1; SMN2KDM4ENPSR1DGAT1 | |
| SCHEMBL1513651 | 0.84 | GRM2 (0.68) | GRM2SMN1; SMN2KDM4ENPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |