Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.59 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903599 | 1.00 | HPRT1 (0.59) | HPRT1TYMPPNPCYP3A4 | |
| SCHEMBL6901396 | 0.82 | HPRT1 (0.59) | HPRT1TYMPPNPCYP3A4 | |
| SCHEMBL6901990 | 0.82 | HPRT1 (0.59) | HPRT1TYMPPNPCYP3A4 | |
| SCHEMBL6901392 | 0.82 | HPRT1 (0.59) | HPRT1TYMPPNPCYP3A4 | |
| SCHEMBL6899234 | 0.76 | HPRT1 (0.57) | HPRT1TYMPPNPCYP3A4 | |
| SCHEMBL6898752 | 0.76 | HPRT1 (0.57) | HPRT1TYMPPNPCYP3A4 | |
| SCHEMBL16038272 | 0.74 | HPRT1 (0.51) | HPRT1TYMPPNP | |
| SCHEMBL9170794 | 0.74 | HPRT1 (0.51) | HPRT1TYMPPNP | |
| SCHEMBL6898763 | 0.73 | HPRT1 (0.64) | HPRT1TYMPCYP3A4 | |
| SCHEMBL4713142 | 0.70 | HPRT1 (0.70) | HPRT1PNPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3561272-B2 | — | — | 2004-09-02 | — | — | JP | claimed |
| US-6653296-B1 | 2-phosphonomethoxypropyl derivatives of purine and pyrimidine bases | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2003-11-25 | — | — | US | claimed |
| EP-0654037-B1 | ANTIRETROVIRAL ENANTIOMERIC NUCLEOTIDE ANALOGS | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1999-05-12 | — | — | EP | claimed |
| EP-0654037-A1 | ANTIRETROVIRAL ENANTIOMERIC NUCLEOTIDE ANALOGS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1995-05-24 | — | — | EP | claimed |
| WO-1994003467-A2 | ANTIRETROVIRAL ENANTIOMERIC NUCLEOTIDE ANALOGS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1994-02-17 | — | — | WO | claimed |
| US-6653296-B1 | 2-phosphonomethoxypropyl derivatives of purine and pyrimidine bases | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2003-11-25 | — | — | US | disclosed |
| EP-0654037-B1 | ANTIRETROVIRAL ENANTIOMERIC NUCLEOTIDE ANALOGS | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1999-05-12 | — | — | EP | disclosed |