Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 4/20 | 0.62 |
| ▸ | RORC | P51449 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.62 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446912 | 0.92 | POLA1 (0.64) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL4432535 | 0.90 | OSBP (0.60) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL7043800 | 0.89 | OSBP (0.66) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL7043798 | 0.89 | OSBP (0.66) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL10334278 | 0.89 | OSBP (0.59) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL10625287 | 0.88 | OSBP (0.58) | OSBPRORCUSP2CYP46A1OSBP2 | |
| Cholesterol SCHEMBL19460624 | 0.87 | OSBP (0.73) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL9122037 | 0.86 | POLA1 (0.57) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL6931519 | 0.86 | POLA1 (0.57) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL9446923 | 0.86 | POLA1 (0.59) | OSBPRORCUSP2CYP46A1OSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328190-B1 | TEMPERATURE MEASURING BALLOON | BOSTON SCIENT LTD (BB) | 2004-12-29 | — | — | EP | claimed |