Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 3/20 | 1.00 |
| ▸ | PGR | P06401 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407673 | 1.00 | ESR1 (1.00) | ESR1ESR2PGR | |
| SCHEMBL407674 | 1.00 | ESR1 (1.00) | ESR1ESR2PGR | |
| SCHEMBL667262 | 1.00 | ESR1 (1.00) | ESR1ESR2PGR | |
| SCHEMBL5070367 | 0.94 | ESR1 (1.00) | ESR1ESR2PGR | |
| SCHEMBL28483063 | 0.94 | ESR1 (1.00) | ESR1ESR2PGR | |
| SCHEMBL5070366 | 0.94 | ESR1 (1.00) | ESR1ESR2PGR | |
| SCHEMBL21512474 | 0.94 | ESR1 (1.00) | ESR1ESR2PGR | |
| SCHEMBL5070365 | 0.94 | ESR1 (1.00) | ESR1ESR2PGR | |
| SCHEMBL1881237 | 0.93 | ESR1 (0.87) | ESR1ESR2PGR | |
| SCHEMBL1881240 | 0.93 | ESR1 (0.87) | ESR1ESR2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417169-A2 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Bristol-Myers Squibb Pharma Company (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016270-A2 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |