Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 4/20 | 0.62 |
| ▸ | RORC | P51449 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.62 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.53 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.51 |
| ▸ | CRYAB | P02511 | 1/20 | 0.51 |
| ▸ | HMGCR | P04035 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625287 | 0.91 | OSBP (0.58) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL7043798 | 0.88 | OSBP (0.66) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL7043800 | 0.88 | OSBP (0.66) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL11656047 | 0.86 | OSBP (0.66) | OSBPRORCUSP2CYP46A1OSBP2 | |
| Cholesterol SCHEMBL21182320 | 0.85 | OSBP (0.75) | OSBPRORCUSP2CYP46A1OSBP2 | |
| Cholesterol SCHEMBL21182319 | 0.85 | OSBP (0.75) | OSBPRORCUSP2CYP46A1OSBP2 | |
| Cholesterol SCHEMBL162271 | 0.85 | OSBP (0.75) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL11656049 | 0.84 | OSBP (0.66) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL2863615 | 0.84 | OSBP (0.63) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL2863613 | 0.84 | OSBP (0.63) | OSBPRORCUSP2CYP46A1OSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328190-B1 | TEMPERATURE MEASURING BALLOON | BOSTON SCIENT LTD (BB) | 2004-12-29 | — | — | EP | claimed |