Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133462 | 1.00 | TSHR (0.42) | TSHRTDP1HPGDALDH1A1TP53 | |
| SCHEMBL10391338 | 1.00 | TSHR (0.42) | TSHRTDP1HPGDALDH1A1TP53 | |
| SCHEMBL8850981 | 1.00 | TSHR (0.42) | TSHRTDP1HPGDALDH1A1TP53 | |
| SCHEMBL6419718 | 0.93 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL4904681 | 0.91 | TSHR (0.46) | TSHRTDP1HPGDALDH1A1TP53 | |
| SCHEMBL28230266 | 0.90 | TSHR (0.44) | TSHRTDP1HPGDALDH1A1TP53 | |
| SCHEMBL11241729 | 0.87 | TDP1 (0.53) | TSHRTDP1HPGDALDH1A1TP53 | |
| SCHEMBL11250054 | 0.87 | TDP1 (0.53) | TSHRTDP1HPGDALDH1A1TP53 | |
| SCHEMBL6909205 | 0.87 | TDP1 (0.53) | TSHRTDP1HPGDALDH1A1TP53 | |
| SCHEMBL5179640 | 0.86 | TDP1 (0.38) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735076-B1 | Process for the production of star-like or comb-like branched aliphatic polyamino compound and curable resin composition | TOYO INK MFG CO (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-5705602-A | Process for the production of star-like or comb-like branched aliphatic polyamino compound and curable resin composition | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0735076-A1 | Process for the production of star-like or comb-like branched aliphatic polyamino compound and curable resin composition | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-4310397-A | SUSTAINED RELEASE; PREPARED BY IRRADIATION POLYMERIZATION | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1982-01-12 | — | — | US | disclosed |
| US-4038264-A | HYDROPHILIC POLYACRYLIC ESTERS, CONTACT LENSES | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-4026826-A | ALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-05-31 | — | — | US | disclosed |
| US-4003991-A | WATER SOLUBLE ACRYLIC, 2-ALKENAMIDE, OR ETHYLENIMINE POLYMER; TOPICAL MEDICAMENTS | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-01-18 | — | — | US | disclosed |